
产品货号:
Z37895
中文名称:
HIF-alpha/HIF1A抗体
英文名称:
Anti-HIF-alpha/HIF1A Antibody (Clone#1A3)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HIF-alpha/HIF1A Antibody (Clone#1A3) |
指标别名 | ARNT interacting protein;bHLHe78;HIF 1 alpha;HIF 1alpha;HIF1;HIF-1;HIF1 ALPHA;HIF1A;HIF-1α;Member of PAS protein 1;MOP1;PASD8 |
克隆性 | Monoclonal |
检验物种 | human,mouse,monkey |
应用范围 | WB,IHC,IF,ELISA |
基因名称 | HIF1A |
克隆号 | 1A3 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human HIF-1alpha expressed in E.Coli. |
计算分子量 | 93KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | HIF-1α (Hypoxia-inducible factor 1α,HIF1A) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced O2 availability in mammals,including angiogenesis,erythropoiesis and glycolysis.This gene was mapped to 14q21-q24.HIF-1α transactivate genes required for energy metabolism and tissue perfusion and is necessary for embryonic development and tumor explant growth.HIF-1alpha is over expressed during carcinogenesis,myocardial infarction and wound healing.It is crucial for the cellular response to hypoxia and is frequently over expressed in human cancers,resulting in the activation of genes essential for cell survival.HIF-1α regulates the survival and function in the inflammatory microenvironment directly.It is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. |
Uniprot ID | Q16665 |
基因名全称 | Hypoxia-inducible factor 1-alpha |
蛋白名全称 | Hypoxia-inducible factor 1-alpha |
推荐稀释比 | WB 1:500~1:2000 IHC 1:200~1:1000 IF 1:200~1:1000 ELISA 1:10000 |
相关搜索:HIF-alpha/HIF1A抗体,HIF-alpha抗体,HIF1A单抗,Anti-HIF-alpha/HIF1A Antibody (Clone#1A3)